For me it depends on the anime.
Most of the time I prefer to listen to the original Japanese cast, but it does give you a bit of a headache always having to read the subtitles.
I remember watching Pokemon and Sailor Moon as a kid and they were always English subbed and so I could never watch them comfortably with the Japanese Cast.
So yeah it just depends on the anime itself and how well they do the Dubs.
Most of the time I prefer to listen to the original Japanese cast, but it does give you a bit of a headache always having to read the subtitles.
I remember watching Pokemon and Sailor Moon as a kid and they were always English subbed and so I could never watch them comfortably with the Japanese Cast.
So yeah it just depends on the anime itself and how well they do the Dubs.