VI was a close second with some of the weird ass characters in it. This is specifying characters, yes?
I have to say this is the reason I think FFVI should be first. I think abouth half the characters in VI brought some comic relief individually and they had good chemistry as well.
Terra's comments about Sabin are priceless.

and in Treno where the Old man said something like "Suicide, at such young age" when Quina jumped to the water.